San Francisco (7-0) at Arizona (3-4-1), 8:20 p.m. on FOX, NFL Network and Amazon. The only unbeaten team in the NFC travels to the desert for a week nine NFC West Thursday night contest in Glendale as San Francisco and Arizona meet at State Farm Stadium.

The 49ers took their seventh win in as many tries last Sunday afternoon at Levis Stadium, taking Carolina to task 51-13 in Wine Country. San Francisco, holding on to first place in the NFC West, led 27-3 at the half and never looked back, holding the Panthers in check for the rest of the contest. Tevin Coleman ran for 105 yards and three TDS in the contest, as the 49ers outrushed Carolina 232-130 (Christian McCaffrey led Carolina with 117 yards and a TD). Jimmy Garoppolo threw for 175 yards and a pair of TDs (one to Coleman, the other to newly accquired WR Emanuel Sanders), despite being sacked three times (one for a safety) and throwing an interception, while Carolina’s Kyle Allen threw for 158 yards, was sacked seven times (three times by rookie LB Nick Bosa) and picked off three times (once by Bosa). San Francisco went 5 of 10 on third down tries and kept the ball for 33:01, while the Panthers, holding the ball for 26:59, went 2 of 13 on third down, 0 for 2 on fourth down.

New Orleans welcomed the return of Drew Brees, then held Arizona to three Zane Gonzalez field goals as they dropped a 31-9 decision in the Big Easy Sunday afternoon. The Desert Angry Birds led 3-0 at the end of the first quarter, then watched as New Orleans erased that lead and Arizona trailed 10-6 at the intermission and would be outscored 21-3 in the final 30 minutes of play at the Mercedes-Benz Superdome. Arizona found themselves held to 40 yards of rushing, while the Saints tallied 137 (Saints RB Latavius Murray led all rushers with 102 yards and a TD), Brees threw for 373 yards and three TDs without a sack (he was picked off once), while Kyler Murray threw for 220 yards with three sacks. New Orleans went 7 of 12 on third down and kept the ball to themselves, ruling the clock for 37:59, while the Desert Angry Birds were 2 of 12 on third down (they went 0 of 2 on fourth down) and held the ball for 22:01.

While the 49ers lead the series 29-26 and have outscored the Desert Angry Birds 1,237-1,123 (including contests that took place in Chicago, St. Louis, Keezar Stadium and Candlestick Park), Arizona has won the last eight meetings in the series, including sweeping last year’s contests (San Francisco’s last win in the series came in 2014, when they left Candlestick Park 20-17 winners).

Their first meeting took place in Santa Clara in week five and it would be Arizona coming away 28-18 winners at Levis Stadium. The Desert Angry Birds led 13-6 at the intermission, then after a scoreless third quarter, outscored San Francisco 14-12 in the final frame. San Francisco did outrush their NFC West foe 147-56 and C.J. Bethard threw for 349 yards and a pair of TDs but threw a pair of interceptions and was sacked four times, while Cardinals QB Josh Rosen threw for 170 yards with a TD and a sack. San Francisco went 10 of 17 on third down tries (they were 1 of 2 on fourth down) and actually ruled the clock, keeping the ball for 40:12, while the Desert Angry Birds, keeping the ball for 19:48, went 2 of 12 on third down tries.

Arizona completed the sweep in the desert in the week eight rematch at State Farm Stadium, rallying in the final seconds to come away 18-15 winners. San Francisco led by a baseball-like score of 5-3 at the half, then watched as Arizona would outscore the 49ers 15-10, with WR Christian Kirk scoring the game-winner with 34 seconds left when he and Rosen connected on a 9-yard TD toss. Rosen, who threw a TD pass to all-pro WR Larry Fitzgerald (8 catches for 102 yards) earlier in the contest, threw for 252 yards, despite being sacked three times with an interception. Bethard threw for 190 yards with a TD for the 49ers in the loss (Bethard was sacked four times). As was the case in the first meeting, the 49ers outrushed Arizona 107-88 and went 5 of 14 on third down tries and once again, they would rule the clock, keeping the ball for 32:19, while the Desert Angry Birds, keeping the ball for 27:41, while going 6 of 14 on third down tries.

In the week five contest in wine country, San Francisco was favored by 4 and the Desert Angry Birds covered with the win by 10 points and both teams covered the 41 over/under with 46 points. In the week eight contest in the desert, the Desert Angry Birds were favored by 1 and covered the spread, winning by 3; however, the 43 1/2 was intract as both teams combined for only 25 points. San Francisco’s favored by 7 1/2 in the desert and the over/under’s 44. Both numbers make a lot of sense. Arizona would love nothing more than to end the 49ers’ win streak, while the 49ers want to keep the streak alive. The streak lives on. San Francisco prevails in the desert and covers the 7 1/2.

Broadcast Information – 8:20 p.m. on FOX, NFL Network and Amazon: Joe Buck, Troy Aikman, Erin Andrews (field reporter), Kristina Pink (field reporter); NATIONAL RADIO: Westwood One: Kevin Kugler, Matt Millen; SIRIUS: 81 (San Francisco), 83 (Arizona); XM: 225 (San Francisco), 226 (Arizona)

Referee: Brad Rogers

Injury Report

San Francisco
DOUBTFUL: T Joe Staley (Fibula)
OUT: RB Kyle Juszczyk (Knee), T Mike McGlinchey (Knee), CB James Witherspoon (Foot)
QUESTIONABLE: RB Matt Breida (Ankle), RB Dominique Mostert (Knee), TE Levine Toilolo (Groin)

Arizona
OUT: DE Zach Allen (Neck), RB Chase Edmonds (Hamstring)
QUESTIONABLE: T Justin Murray (Knee), RB David Johnson (Ankle)

Weather Forecast: Game Indoors; if roof is open, sunny and 73 degrees

Broadcast information, officials and injury report courtesy the National Football League, odds courtesy Don Best, weather information courtesy The Weather Channel