Tennessee (1-1) at Jacksonville (0-2), 8:20 p.m. on NFL Network. A pair of AFC South rivals meet in the Sunshine State as Tennessee and Jacksonville, both coming off losses last week, open play in week 3.

Last week, Derrick Henry had 81 rushing yards and a touchdown in Tennessee’s Week 2 loss at home against Indianapolis. He enters Thursday night with at least 80 rushing yards in six consecutive games, the longest active streak in the NFL. Quarterback Marcus Mariota has five touchdowns and no interceptions over his past three road games, including throwing for three touchdowns and no interceptions with a 133.3 rating in Tennessee’s 43-13 Week 1 win at Cleveland. Rookie wide receiver A.J. Brown leads the team with 125 receiving yards through the season’s first two weeks, second-most among AFC rookies. Cornerback Logan Ryan has an interception in each of the first two games of the season, while safety Kevin Byard’s 13 interceptions since 2017 are the most in the NFL during that span. Tennessee enters Week 3 leading the league with a +5 turnover differential.

Jacksonville rookie quarterback Gardner Minshew comes into Thursday night off his first career start, throwing for 213 yards and a touchdown and rushing for a team-high 56 yards in the Jaguars’ Week 2 loss. The sixth-round draft choice saw his first action in Week 1, when he completed 88 percent of his passes (22 of 25), the highest completion percentage by a quarterback in his NFL debut in league history (minimum 15 attempts). He also completed his first 13 pass attempts, the longest streak to begin a career over the past 40 seasons. Wide receiver D.J. Chark enters the game as Jacksonville’s leading receiver, registering 201 yards and two touchdowns over the season’s first two weeks. Cornerback Jalen Ramsey leads the Jaguars in interceptions (nine) and has the fourth-most passes defensed (45) in the NFL since entering the league in 2016.

Tennessee trailed Indianapolis 13-7 at the half, then took their only lead of the contest when Henry and K Carlos Santos helped their team put 10 third-quarter points on the board to take a 17-13 lead with 4:35 left in the period. That lead would not last long as the Colts would reclaim it for themselves and for keeps with 4:38 left in the contest when QB Jacboy Brissett and WR T.Y. Hilton connected on a 4-yard TD toss. The Titans would catch a huge break when Colts K Adam Vinatieri missed the extra point, giving them a chance to take the win at home. After the Colts punted the ball late in the fourth, Tennessee would make their way down the field and get as close as Indianapolis’ 45-yard line, where the drive stalled and the Colts would come away with the win.

The Colts outrushed Tennessee 167-123 and Mariota threw for 154 yards and a TD (he was sacked four times but did not throw an interception), while Brissett threw for 146 yards with three TDs (including the game-winner) to go with four sacks and an interception. Tennessee was a somewhat dismal 1 of 10 on third down conversions (they were 0 of 1 on fourth down) and the Titans would hold on to the ball for 28:06, while the Colts were 7 of 14 on third down, 1 of 1 on fourth down and ruled the clock as they would keep the ball for 31:54.

The Jaguars are in search of their first win of the 2019 campaign and comes back to the Sunshine State after their 13-12 AFC South loss at Houston last Sunday. Jacksonville trailed 6-3 at the intermission and made it a 1-point contest with 30 seconds left in the contest when Minshew and Chark connected on a 4-yard TD toss. Jacksonville would then miss the two-point conversion at NRG Stadium and went for the on-side kick, which Houston recovered. The Texans would then go on to run out the clock and take the win. Houston out-rushed Jacksonville 126-103 and Minshew threw for 213 yards with the late contest TD, while DeSean Watson threw for 159 yards without a TD (both men were sacked four times but neither threw an interception). While Jacksonville was 3 of 13 on third down and the Texans were 6 of 15, both teams had success on fourth down tries, with Jacksonville going 2 of 2 and Houston going 1 of 1. Jacksonville actually ruled the clock and kept the ball for 30:01 to Houston’s 29:59.

The Titans lead the series 28-20 (which includes contests that were played in Houston when they were known as the Oilers), have outscored Jacksonville 995-903 and have won the last four meetings in the series, including sweeping the series in 2018 (Jacksonville’s last win came in 2016 in the Sunshine State by a final of 38-17).

Their first meeting was week three in Jacksonville and it was the kickers on display as Josh Lambo and Ryan Succop exchanged field goals in that contest. It would be Succop that would get the last word as he broke a 6-6 tie by nailing a 28-yard try with 4:06 left in the contest to give Tennessee a 9-6 win at TIAA Bank Field. Tennessee out-rushed Jacksonville 150-87 and Mariota threw for 100 yards, while Blake Bortles threw for 155 yards (Bortles was sacked three times, Mariota was sacked once; neither threw an interception). Jacksonville was 5 of 15 on third downs, 0 of 1 on fourth down and the Jaguars would hang on to the ball for 27:13, while Tennessee ruled the clock, keeping the ball for 32:47 and the Titans went 5 of 15 on third down tries.

The Titans completed the sweep of the series in the Music City and they would take care of business in week 14 in Nashville by a final of 30-9 at Nissan Stadium. Tennessee led 16-2 at the intermission, then went on to outscore the Jaguars 14-7 in the third (the two teams played a scoreless fourth quarter). The Titans out-rushed Jacksonville 264-60 with Tennessee’s Derrick Henry leading the way with 238 yards and four TDs, while Mariota threw for 162 yards (Jacksonville’s Cody Keesler threw for 240 yards and a TD toss to Dede Westbrook but was sacked four times and threw an interception). The Titans went 7 of 11 on third down (they were 0 for 1 on fourth down) and kept the ball for 29:20, while the Jaguars were rulers of the clock, holding the pigskin for 30:40 and went 2 of 12 on third down, 2 of 5 on fourth down.

Jacksonville was favored by 3 in the week three contest in the Sunshine State but the Titans’ 3-point win meant that they did not cover and the 40 over/under was safe as both teams combined for only 15 points. Tennessee easily covered the 4-point spread in the week 14 contest and the 39 points barely covered the 37 1/2 over/under. The Titans may be the road team but the boys and girls in Las Vegas have made them a 1-point with a 39 over/under. Tennessee covers the 1 and wins in the Sunshine State Thursday night.

Broadcast Information – 8:15 p.m. Joe Buck, Troy Aikman, Erin Andrews (field reporter), Kristina Pink (field reporter); NATIONAL RADIO: Westwood One: Ian Eagle, Rod Woodson; SIRIUS: 81 (Tennessee), 83 (Jacksonville); XM: 225 (Tennessee), 226 (Jacaksonville)

Referee: Shawn Hochuli

Injury Report

Tennessee
OUT: RB David Fluellen (Hamstring, CB Chris Milton (Collarbone), G Kevin Pamphile (Knee)
QUESTIONABLE: LB Wesley Woodyard (Quadricep)

Jacksonville
OUT: LB Donell Alexander (Hamstring), TE Josh Oliver (Hamstring)
QUESTIONABLE: CB Joshua Robinson (Foot), CB Arlandrus Bouye (Hip)

Weather: Partly cloudy and 77 degrees

Broadcast information, officials and injury report courtesy the National Football League, odds courtesy Don Best, weather information courtesy The Weather Channel.