Carolina (6-2) at Pittsburgh (5-2-1), 8:20 p.m. on FOX, NFL Network and Amazon. Week 10 opens in the Steel City as Ben Roethlisberger and the Pittsburgh Steelers host Cam Newton and the Carolina Panthers at Heinz Field. Both teams took major divisional wins in last Sunday’s action, with Carolina winning at home, while the Steelers were road victors.

The Panthers, in picking up their third win in a row, took a 35-14 lead with them to the intermission against Tampa Bay last Sunday at Bank of America Stadium and came away 42-28 winners over their NFC South rivals. The Panthers outrushed Tampa Bay 179-82 (Carolina’s Christian McCaffrey led all rushers with 79 yards and a pair of rushing TDs), while Newton threw for 247 yards and a pair of TDs. Carolina, who sacked Tampa Bay QB Ryan Fitzpatrick (243 yards, four TDs, two interceptions) four times, went 4 for 10 on third down (they were 0 of 1 on fourth down) and held the ball for 31 minutes, while the Buccaneers kept the ball for 29 minutes, going 5 for 12 and 1 of 2 on third and fourth downs.

Pittsburgh got their revenge on Baltimore from their week four loss to Baltimore at Heinz Field and took down the Ravens 23-16 at M&T Bank Stadium in Charm City, giving the Ravens their third loss in a row. Pittsburgh led 14-6 at the intermission, then held off the Ravens as they were outscored by Baltimore 10-9 in the final 30 minutes of action. Pittsburgh outrushed Baltimore 113-61, with Steelers RB James Conner leading everyone with 107 yards. Roethlisberger threw for 270 yards and a pair of TDs (one to Antonio Brown, the other to Conner), while Joe Flacco led Baltimore with 209 yards (Roethlisberger was sacked once, Flacco was sacked twice; neither man threw an interception). Pittsburgh was 10 for 16 on third down tries and kept the ball for 36:29, while the Ravens, who held the pigskin for 23:31, went 4 for 12 on third down, 0 for 1 on fourth down.

Pittsburgh leads the series 5-1, the Steelers have outscored Carolina 175-77 and after Carolina won the first meeting, taking an 18-14 win in Charlotte in 1996, Pittsburgh has won five in a row, with their last win coming in 2014 in Charlotte by a final of 37-19. The odds makers in Vegas like the Steelers at home as a 4-point favorite on Thursday night and the over/under’s 52. Both numbers make sense and both Newton and Roethlisberger could put the over/under up by the end of the 3rd quarter. These two are playoff contenders, which could very well mean that we will see them come January. Carolina makes it closer than the 4 but the Steelers take the win in the Steel City.

Broadcast Information – 8:20 p.m. on FOX, NFL Network and Amazon Prime: Joe Buck, Troy Aikman, Erin Andrews (Field reporter), Kristina Pink (Field reporter); NATIONAL RADIO: Westwood One: Ian Eagle, Tony Boselli; SIRIUS: 81 (Carolina), 83 (Pittsburgh); XM: 226 (Carolina), 225 (Pittsburgh)

Referee: Walt Coleman

Injury Report

Carolina
OUT: DE Marquis Haynes (Illness), WR James Smith (Knee)
QUESTIONABLE: C Ryan Kalil (Ankle), DE Mario Addison (Shoulder), LB David Mayo (Groin), S Eric Reid (Shoulder)

Pittsburgh
OUT: T Marcus Gilbert (Knee), DT Daniel McCullers (Ankle)

Weather: Partly cloudy and 40 degrees

Broadcast Information and Injury Report courtesy the National Football League, odds courtesy Don Best, weather information courtesy The Weather Channel. (Note: Weather information is based on kickoff local time)