Philadelphia (2-3) at New York Giants (1-4), 8:20 p.m. on FOX and NFL Network. The two teams don’t like each other. The same can be said for the two cities. A pair of NFC East rivals meet in upstate New Jersey to open play in week six when the defending Super Bowl champs take on Eli Manning and the New York Giants at Met Life Stadium. Both divisional foes took close losses last week and are looking to regroup.

A Philadelphia rally in the second half fell short against Minnesota as they fell to the Vikings 23-21 at Lincoln Financial Field in a rematch of last year’s NFC Championship game. Minnesota led 17-3 at the half before the defending Super Bowl champrs would go on to outscore the Vikings 18-6 in the final 30 minutes of action. The Vikings broke a 3-3 tie with 4:12 left before the intermission when Vikings DL Linval Joseph lived a lineman’s dream as he picked up a Carson Wentz fumble and returned it 64 yards for a TD to take the lead. WR Adam Thielen and QB Kirk Cousins would then tack on a 3-yard TD pass before the intermission to give the Vikings a 17-3 at that point. Philadelphia would chip away at Minnesota’s lead, pulling to within two with 69 seconds left when TE Zach Ertz and Wentz connected on a 7-yard TD toss. Philadelphia’s onside kick failed as the Vikings recovered and ran out the clock. Philadelphia outrushed Minnesota 81-77 and Wentz threw for 311 yards with a pair of TDs, while Cousins threw for 301 yards with a TD (neither man threw an interception, Wentz was sacked three times, Cousins sacked once). Philadelphia was 2 of 9 on third down but found success on their only fourth down try and kept the ball for 27:13, while the Vikings ruled the clock, holding the ball for 32:47, going 4 of 11 on third down to take the 2-point win.

Manning and the Giants saw Carolina and Graham Gano take victory from their hands last Sunday in Charlotte, falling on the short end of a 33-31 loss at Bank of America Stadium. Trailing 20-10 at the intermission, the Giants would later pull their way into the lead when Manning and WR Odell Beckham caught a 33-yard TD pass with 8:08 left in regulation (Beckham, who had eight catches for 131 yards, threw a 57-yard TD pass to rookie RB Sequan Barkley earlier in the game, became the first player to have a TD pass and catch in the same contest since Mark Clayton did it for Baltimore in week eight in 2008). Gano would give the Panthers the lead back with 2:16 left, booting a 39-yard try before Manning and Barkley connected on a 15-yard TD toss with 65 seconds left. Carolina would then drive almost the length of the field with no time outs, using an 8-play, 30-yard drive that used 67 seconds of clock, allowing Gano to kick the game winner with one second left on the clock. Carolina outrushed Big Blue 118-50 and Manning threw for 326 yards and a pair of TDs, while Cam Newton threw for 237 yards and a pair of TDs (one to Collin McCaffery, the other to Curtis Samuel; both Manning and Newton threw a pair of interceptions and both were sacked once). The Giants found themselves going 0 of 7 on third down (1 of 2 on fourth down) and held on to the ball for 24:33, while Carolina ruled the clock and held the pigskin for 35:27, going 4 of 13 and 1 of 1 on third and fourth down tries.

Including contests that took place at Yankee Stadium, the Yale Bowl, JFK Stadium, Giants Stadium and Veterans Stadium, the Giants lead the series 83-81-2 and have outscored the Eagles 3,206-3,150. The Eagles have won the last three meetings in the series, including sweeping the series last year (New York’s last win came in 2016 in the Meadowlands by a final of 28-23).

The first meeting? The City of Brotherly Love in week three. The Eagles led 7-0 at the break and took a 14-0 lead at the end of the third quarter and had to survive a late Giants charge in the fourth quarter to take a 27-24 win. Philadelphia secured the contest thanks to a 61-yard field goal by Josh Elliott as the clock struck :00. The Giants used three Manning TD passes in the fourth quarter (two to Beckham, the other going to Russell Shepherd) and an Aldrick Rosas field goal to take a 24-21 lead. Elliott would tie things with a 46-yard field goal with 51 seconds left before kicking the game winner 51 seconds later. Philadelphia out-rushed Big Blue 193-49, with Carson Wentz throwing for 176 yards and a TD (Wentz was sacked three times), while Manning threw for 366 yards with a pair of interceptions to go with the three TDs. Philadelphia found themselves going 5 for 14 on third down (they were 2 of 3) and they kept the ball for 37:32, while the Giants were 3 of 10 on third down (0 of 2 on fourth down) and held the ball for 22:28.

Philadelphia completed the sweep in the Meadowlands in week 15 as they erased a 23-21 deficit at the intermission and came away with the 34-29 win. The Eagles would go on to outscore the Giants 13-6 in the final 30 minutes of action at Met Life Stadium to seal the deal and New York’s fate in the process. The Giants would eventually pull themselves to within 2 with 1:57 left when Manning and Tavares King connected on a 57-yard strike (they would miss the extra point) before the Eagles restored order when Elliott booted a 20-yard field goal with 3:56 left in the contest. The Eagles out-rushed the Giants 108-75 and Manning threw for 434 yards and three TDs, while Nick Foles, taking over for the injured Wentz, threw for 237 yards with four TDs (each man was sacked once). Philadelphia went 6 of 13 on third down tries in the Meadowlands (they were 0 for 1 on fourth down) and kept the ball for 30:53, while the Giants were 10 of 18 on third down, 0 of 1 on fourth down and held on to the ball for 29:07.

In the week three contest in Philly, the Eagles were favored by 6 but would wind up winning by 3. Both clubs did manage to take care of the 48 1/2 over/under by tallying 51 points. In the rematch in the Meadowlands that allowed the Eagles to sweep the series, Philly was favored by 7 1/2 but won by 5. The 40 over/under was easily covered as the two clubs merged for 63 points. The Eagles are favored by 3 and the over/under’s 44. Both teams are struggling in the NFC East and the loser of this will have to work harder to keep their heads above water. For the winner? Redemption from a loss from last week. Eagles cover the 3 and win in the Meadowlands.

Broadcast Information: 8:20 p.m. on FOX/NFLN/Amazon: Joe Buck, Troy Aikman, Erin Andrews (Field reporter), Kristina Pink (Field reporter); NATIONAL RADIO: Westwood One: Ian Eagle, Tony Boselli; SIRIUS: 81 (Philadelphia), 83 (New York Giants); XM: 226 (Philadelphia), 225 (New York Giants)

Referee: Ron Torbert

Injury Report

OUT: LB Donell Alexander (Quadricep), S Corey Graham (Hamstring), DT Etuini Ngata (Calf), RB Darren Sproles (Hamstring)

New York Giants
OUT: WR Russell Shepard (Neck), TE Evan Engram (Knee)
QUESTIONABLE: TE Rhett Ellison (Foot)

Weather – Overcast with a 60 percent chance of thunderstorms and 73 degrees

Broadcast Information and Injury Report courtesy the National Football League, odds courtesy Don Best, weather information courtesy The Weather Channel. (Note: Weather information is based on kickoff local time)