Denver (4-9) at Indianapolis (3-10), 8:25 p.m. on NBC, NFL Network and Amazon Prime. A pair of AFC teams with almost no playoff hopes open action in week 15 as the Indianapolis Colts return to Indianapolis to face off against the Denver Broncos.

Denver aims for its second consecutive win after defeating the New York Jets 23-0 in Week 14. The Broncos led 13-0 at halftime at Sports Authority Field, then added more fuel to the fire by scoring their last 10 points of the contest unchallenged. Denver outrushed the Jets 84-59 and held Josh McCown to 46 yards passing, sacking him four times and knocking him out of the contest with a broken hand, while Trevor Siemian threw for 200 yards, connecting with WR Demaryius Thomas on a 20-yard TD strike in the first quarter. Denver went 7 of 17 on third down (1 of 1 on fourth down) and kept the ball for 37:35, while New York was 3 of 13 and 0 of 1 on third and fourth down tries, keeping the pigskin for 22:25.

The Colts return home from chilly and snowy Buffalo and looks to rebound following a 13-7 overtime loss at Buffalo last week. Colts running back Frank Gore rushed for 130 yards at New Era Stadium in a contest that was played pretty much in a blizzard (game time temperature? 32 degrees with snow and a wind chill of 16) in upstate New York. Indy trailed 7-0 at the break, then tied things up with 76 seconds left in regulation when TE Jack Doyle and QB Jacoby Brissett connected on a 3-yard TD strike, sending the contest into overtime. Buffalo won the toss in overtime but failed to score in their first possession and the Colts did likewise when they had the ball in the overtime.

The Bills then got the ball back after a Colts punt with 2:25 left in the extra period and they wasted little time to take the win, using a five-play, 65-yard drive that took 52 seconds, sending their fans home happy if not warm when LeSean McCoy dashed through the snow and scored from 21 yards out to take the win. Buffalo rushed for 227 yards (McCoy led all rushers with 156 yards), while the Colts tallied 163 in the overtime loss. Brisset threw for 65 yards while Nick Peterman threw for 57. The Colts went 4 of 16 on third down, 3 of 4 on fourth down and held the ball for 36:02, while Buffalo kept the pigskin for 32:25, going 10 of 18 on third down and 0 of 1 on fourth down.

Denver leads the regular season series 13-10 (including games that took place in Baltimore) and the Broncos have outscored the Colts 526-483 in those contests. Denver won the last meeting with the Colts in the Mile High City last year, taking a 34-20 win last year (Indy’s last win over the Colts came in 2015 in the Hoosier State by a final of 27-24).

They met in week 2 at Sports Authority Field at Mile High and the Broncos broke a 3-3 first quarter tie, taking a 13-6 lead with them to the break, then outscoring the Colts in the second half by a 21-14 margin. Denver outrushed Indy 134-83, Siemian threw for 266 yards for Denver, while Andrew Luck threw for 197 yards with a TD but was sacked five times and picked off once. Denver was 5 of 11 on third down and the Broncos ruled the clock and kept the ball for 30:41, while the Colts went 6 of 14 on third down, 1 of 1 on fourth down and held the ball for 29:19.

In the week two contest in the Rocky Mountains, Denver was favored by 6 and covered the spread, winning by 14. Both clubs combined for 54 points, covering the 46 over/under. In the Thursday evening contest in Indy, Denver’s favored by 1 1/2 and the over/under is 40 1/2. It’s safe to say that neither team will reach the .500 mark or will be going to the post-season, so feel free to watch “Big Bang Theory” and “Scandal” this week. Denver covers the 1 1/2 and wins in the Hoosier State.

Broadcast Information – 8:25 p.m. on NBC, NFL Network and Amazon Prime: Mike Tirico, Cris Collinsworth, Heather Cox (Field reporter); NATIONAL RADIO: Westwood One: Kenny Albert, Tony Boselli; SIRIUS: 88 (WestWood1), 81 (Denver), 83 (Indianapolis);| XM: 88 (WestWood1), 81 (Denver), 83 (Indianapolis)

Referee: Terry McAulay

Injury Report

OUT: QB Paxton Lynch (Ankle)
QUESTIONABLE: DT Domata Peko (Knee)

OUT: WR Donte Moncrief (Ankle), C Ryan Kelly (Concussion), TE Darrell Daniels (Hamstring), CB Nathan Hairston (Concussion), CB Rashaan Melvin (Hand)

Weather Information: Game indoors; if roof is open, cloudy and 27 degrees

Broadcast information, officials and injury report courtesy the Nation Football League, odds courtesy Don Best, weather information courtesy The Weather Channel