Arizona (1-3) at San Francisco (1-3), 8:25 p.m. on CBS, NFL Network and Twitter. A pair of NFC West rivals, sitting in the division cellar, meet in wine country Thursday afternoon to open play in week five. Both teams enter the NFC West contest with losses under their belts.

Arizona led Los Angeles 13-10 at the end of 45 minutes of play before the Rams rallied to take the lead with a 4 yard TD pass from Case Keenum to WR Brian Quick with 2:36 left in regulation, giving the Rams a 17-13 win in Glendale. Arizona and Los Angeles were tied 10-10 at the half before the Desert Angry Birds took the lead on a 21 yard fieid goal by Chandler Catanzaro as the third quarter came to an end.

While Arizona ran for 118 yards, they held Los Angeles to 41 in the contest and Carson Palmer threw for 288 yards and a TD (he was sacked three times) before leaving the contest with a shoulder injury. Keenum threw for 266 yards and a pair of TDs, both to Quick, including the game-winner. Arizona, who turned the ball over five times, went 6 of 13 on third down tries and kept the ball for 32:09, while the Rams were 6 of 14 and 0 of 1 on third and fourth downs, keeping the pigskin for 27:51.

San Francisco was also tied at the half on Sunday, as they squared off against the Tony Romo-less Dallas Cowboys in Santa Clara last Sunday. Dallas erased a 14-14 tie at the intermission and came away 24-17 winners at Levi’s Stadium. Cowboys rookie RB Ezekiel Elliot (TD) ran for 138 of his team’s 194 yards, while San Francisco tallied 106, while 49ers QB Blaine Gabbard threw for 196 yards with a TD, sack and an interception. For Dallas, rookie QB Dak Prescott threw for 245 yards and a pair of TDs on the West Coast. San Francisco was 8 of 14 and 0 of 1 on third and fourth down conversions and kept the ball for 23:33, while Dallas ruled the clock, holding the ball for 36:27 and going 6 of 14 on third down tries.

San Francisco leads the 29-20 (which includes contests that were played at Keezar Stadium, Candlestick Park in San Francisco and old Busch Stadium in St. Louis) and the 49ers have outscored the Desert Angry Birds 1,138-983. But…. Arizona won the last two meetings, including sweeping last year’s series, taking wins in northern California and in the desert (San Francisco’s last win over Arizona came in 2014, when they were 20-17 winners at Candlestick Park).

Week three… Glendale. San Francisco was manhandled by Arizona 47-7. Colin Kaepernick scored the 49ers’ lone TD, a 12 yard run with 2:03 left before halftime. Arizona led 31-7 at the half and were never threatened by San Francisco after that. Arizona RB Chris Johnson (2 TDs) ran for 110 of his team’s 139 rushing yards in the contest, while San Francisco ran for 103. The Arizona defense managed to sack Kaepernick (67 yards passing) twice and picked him off four times in the lopsided contest, while Palmer threw for 311 yards, connecting with All-Pro WR Larry Fitzgerald on a pair of TD strikes. Arizona went 6 of 13 and 1 of 1 on third and fourth down conversions in the desert, keeping the ball for 36:32, while San Francisco kept the pigskin for 23:28, going 4 of 12 on third down.

Round two… Santa Clara in week 12. This time, things were closer for 49ers fans and that was the good news. The bad news? They came up short, losing to Arizona 19-13. Leading 6-3 after 15 minutes of action, the Desert Angry Birds needed to hold off a San Francisco rally that made the contest a bit too close for their liking when they tied things up at 13-13 with a 33 yard field goal by Phil Dawson with 1:28 left in the third quarter. Arizona would eventually take the lead back and for good when Palmer (271 yards) took it in himself from eight yards out with 2:28 left in regulation. This time, neither team breached the 100-yard barrier but Arizona did somehow manage to outrush San Francisco 70-67 and Blaine Gabbert, subbing for Kaepernick, threw for 318 yards in a losing cause. San Francisco, who turned the ball over twice in the loss, was 0 of 9 on third down tries (1 of 2 on fourth down) and kept the ball for 22:33, while Arizona was 7 of 14 and 0 of 1 on third and fourth downs, keeping the ball for 37:27.

The oddsmakers like Arizona on the road as 4 point favorites and the over/under’s 43 1/2. Both numbers make sense and both teams are somewhat bad, so if you decide that watching “Grey’s Anatomy” and “How To Get Away With Murder” this week is for you, we’re not going to hold it against you. The boys and girls in Vegas like the Desert Angry Birds and the favorite and we agree with them. Arizona covers the 4 and wins this one in Napa Valley.

At 6 p.m. on NFL Network, TNF GameDay Presented by KFC previews the Cardinals-49ers matchup from NFL Network’s studios in Los Angeles. Host Rich Eisen is joined by analysts Steve Mariucci, Marshall Faulk and Michael Irvin to provide news and analysis two hours before kickoff, while host Amber Theoharis and analyst LaDainian Tomlinson join from outside Levi’s Stadium. Reporters Tracy Wolfson and Steve Wyche join to provide the latest news leading up to kickoff.

At 7:30 p.m. on CBS, NFL Network and Twitter, NFL Thursday Night Kickoff airs from inside Levi’s Stadium with James Brown, Deion Sanders and Bill Cowher. Coverage continues at 8:00 PM ET with NFL Thursday Night Kickoff Presented by Tostitos providing the final say leading up to kick-off between Cardinals-49ers.

Among the pregame topics are:
•Feature on veteran Cardinals star defensive lineman Calais Campbell, providing a glimpse into his life and family. Campbell was raised in Denver with seven brothers and sisters, nearly all of whom have moved to the Phoenix area to be close together
•Deion Sanders and Bill Cowher take to the field to break down the gameplan for Cardinals quarterback Drew Stanton
•Essay by NFL Network’s Steve Wyche on 49ers quarterback Colin Kaepernick’s social impact
•How do the Cardinals get back on track?
•How do the 49ers replace linebacker NaVorro Bowman?

At halftime, Brown, Sanders and Cowher break down the first half on the Lexus Halftime show.

Immediately following the game, the Mazda Postgame show airs live on NFL Network, CBS and Twitter from both Los Angeles and Levi’s Stadium providing highlights, analysis and live interviews.

Twitter will stream CBS’s broadcast of Cardinals-49ers, providing free, live streaming video on the Twitter platform on mobile phones, tablets, PCs and connected TVs. Fans can visit Twitter Moments or to view the live stream.

The entire 18-game Thursday Night Football schedule, including the live games and pre- and postgame shows, will also be streamed live on the NFL Mobile from Verizon app (, the NFL app on XBOX, including interactive features from Microsoft, and through Watch NFL Network on tablets, PCs and various connected TV devices (, with participating television providers. Learn all of the ways to watch at An audio broadcast of the game is available on SiriusXM, TuneIn & Westwood One Radio Sports.

Thursday Night Football is available in Spanish via SAP (Secondary Audio Program) with Roberto Abramowitz calling the action on CBS and NFL Network.

Broadcast Information – 8:25 p.m. on CBS, NFL Network and Twitter: Jim Nantz, Phil Simms, Tracy Wolfson (Field
reporter). Westwood One: Ian Eagle, Mike Holmgren. SIRIUS: 88 (WestWood1), 83 (Arizona), 81 (San Francisco). XM: 88 (WestWood1), 226 (Arizona), 225 (San Francisco).

Referee – Carl Cheffers.

Injury Report

OUT: TE Darren Fells (Shoulder), QB Carson Palmer (Concussion), DT Edward Stinson (Toe)
QUESTIONABLE: CB Justin Bethel (Foot), DT Josh Mauro (Chest), DT Frostee Rucker (Knee)

San Francisco
OUT: LB Navorro Bowman (Achilles), DT DeForest Buckner (Foot), CB Jimmie Ward (Quadricep)
QUESTIONABLE: DT Glenn Dorsey (Knee), WR Jeremy Kerley (Ankle), TE Vance McDonald (Hip)

Weather Forecast: Sunny and 74 degrees.

Broadcast Information, officials and Injury report courtesy the National Football League, odds courtesy Don Best, weather information courtesy The Weather Channel.