Seattle (2-3) at San Francisco (2-3), 8:25 p.m. Eastern Thursday on CBS and NFL Network. A pair of NFC west rivals meet in northern California as the Seattle Seahawks make the trip down I-5 to face off against San Francisco in the week 7 opener at Levis’ Stadium.

It’s “What’s your deal?” without Jim Harbaugh. He’s now at Michigan and Pete Carroll remains in the land of grunge, salmon and Starbucks.

Seattle and San Francisco have split the previous 10 games, with each team claiming five wins apiece.

San Francisco enters Week 7 following a 25-20 victory over Baltimore. The victorious 49ers led 16-6 at the break and then managed to hold off the Ravens in the second half for the win.

49ers quarterback Colin Kaepernick passed for 340 yards and two touchdowns for a 128.2 passer rating in the victory. The 49ers veteran wide receiver duo of Anquan Boldin and Torrey Smith served as reliable targets for Kaepernick on Sunday. Boldin had five receptions for 102 yards and Smith had three catches for 96 yards and a touchdown. Although they were held to 65 yards rushing by the Ravens, who tallied 77, the 49ers managed to play turnover-free football in Santa Clara last Sunday. The 49ers were 5 of 13 on third down tries and kept the ball for 26:53, while the Ravens were 4 of 13 on third down, 1 of 1 on fourth down and kept the ball for 33:07.

“Anything positive we can get, we have to keep it going right now and take it one game at a time,” says Smith, who has recorded at least 90 receiving yards in three of his past four games on Thursday. “We can’t spend too much time being happy about this. We have a tough defense coming in on Thursday. We have to get our minds right for that game.”

Boldin enters Thursday’s game with four 100-yard receiving games against Seattle. He also has 86 receptions and 1,079 receiving yards against Seattle during his career, both the fourth-most totals for a Seahawks opponent all-time. With six receptions on Thursday night, Boldin would surpass Torry Holt (91) for the third-most career receptions against Seattle.

The career receiving leaders against Seattle:
Larry Fitzgerald – Arizona (116)
Tim Brown – Oakland, Tampa Bay (114)
Torry Holt – St. Louis, Jacksonville (91)
Anquan Boldin – Arizona, Baltimore, San Francisco (86)

Tim Brown – Oakland, Tampa Bay (1,686)
Larry Fitzgerald – Arizona (1,504)
Torry Holt – St. Louis, Jacksonville (1,247)
Anquan Boldin – Arizona, Baltimore, San Francisco (1,079)

Anquan Boldin – Arizona, Baltimore, San Francisco (5.7)
Torry Holt – St. Louis, Jacksonville (5.7)
Larry Fitzgerald – Arizona (5.5)
Wes Chandler – New Orleans, San Diego, San Francisco (5.1)
Tony Martin – Miami, San Diego (4.8)

Torry Holt – St. Louis, Jacksonville (77.9)
Tony Martin – Miami, San Diego (74.4)
Derrick Alexander – Cleveland, Baltimore, Kansas City, Minnesota (74.1)
Wes Chandler – New Orleans, San Diego, San Francisco (72.3)
Anquan Boldin – Arizona, Baltimore, San Francisco (71.9)

*minimum 8 games played

Seattle enters Week 7 following a 27-23 loss to Carolina. The defending NFC champs let a 20-14 lead after three quarters get out of their hands as the Cam Newton-led Panthers outscored Seattle 13-3 in the final 15 minutes of action in the land of grunge, salmon and Starbucks. Carolina outrushed Seattle 135-115 and Newton threw for 269 yards and a pair of TDs, while rushing for a TD himself early in the contest. Neither club did much on third down tries (Carolina was 4 of 11 and 0 of 1 on fourth down) and held the ball for 32:12, while the Seahawks were 4 of 14 and kept the pigskin for 27:48.

“Unfortunately, we are challenged by this loss,” says Seahawks head coach Pete Carroll. “The important thing is now not what just happened but how we handle it. These guys will hang and work together to bring a really good effort on Thursday.”

Seattle quarterback Russell Wilson passed for 241 yards against Carolina, including a 40-yard touchdown pass to wide receiver Ricardo Lockette in the third quarter. Seahawks tight end Jimmy Graham added eight catches for 140 yards, the third-best total of his career (179 yards, New Orleans at Tampa Bay; 146 yards, New Orleans vs. Atlanta).

“Fortunately we have a short week this week,” Wilson told KIRO-TV and KING-TV. “We get to play on Thursday night against a very tough football team. We’ll go on the road. All we know to do is to pull the reigns together and go to battle together.”

Wilson heads into this week’s matchup having won his past three starts in Thursday games, passing for six touchdowns with no interceptions for a 117.2 passer rating. Including the postseason, Wilson has also led the Seahawks to victories in five of its past six games against San Francisco.

Wilson’s career numbers against San Francisco (including postseason):

The Seahawks lead the series 17-15, have outscored the 49ers 747-590 and have won three of the last four regular season meetings with San Francisco, including sweeping the series in 2014 (San Francisco’s last win came in 2013, when they won 19-17 at old Candlestick Park).

They met in week 13 in Santa Clara on Thanksgiving night at Levi’s Stadium and the Seahawks held San Francisco to a third-quarter field goal to take a 19-3 win over the 49ers. Seattle outrushed the 49ers 157-64 (with Marshawn Lynch running for 104) and sacked Colin Kaepernick four times and forced three San Francisco turnovers. Both clubs on third down tries were at 36 percent (Seattle was 5 of 14, San Francisco was 4 of 11) and Seattle was 0 of 1 on fourth down conversions in the Thursday night contest. Seattle ruled the clock, holding the ball for 35:19 to the 49ers’ 24:41.

Two weeks later… week 15… things moved to Seattle’s CenturyLink Field, in the land of grunge, salmon and Starbucks. Lynch was again in “Beast Mode,” rushing for 91 yards and a TD as the Seahawks took San Francisco to task 17-7. Seattle erased a 7-3 deficit at the half and scored their last 14 points in the second half unchallenged. Seattle outrushed 152-140 and gave Kaepernick a hard time in the second contest, sacking him six times, while Wilson was sacked five times. Seattle did much better on third down conversions at home, going 8 of 14 and held the ball for 28:58, while San Francisco held on to the ball for 31:02, going 6 of 15 on third down, 2 of 4 on fourth down.

San Francisco in the week 13 Thanksgiving night contest was favored by 1 and Seattle covered the spread with ease, winning by 16. The bad news was that both teams probably overdid the Thanksgiving Day meal and could not cover the 39 1/2 over/under, scoring only 22 points. Seattle in the week 15 contest in the Pacific Northwest barely covered the 9 1/2 point spread with their 10-point win and the 38 1/2 over/under was untouched, as Seattle and San Francisco scored only 29 points.

This time, the Seahawks are favored by 4 with a 41 over/under. Both teams have been struggling of late and both are trying to catch Arizona in the NFC West (some are calling the divison “The Mild, Mild West). San Francisco makes it closer than 4 but Seattle continues its winning ways over the 49ers and takes this one in northern California.

BROADCAST INFORMATION: CBS/NFLN at 8:25 p.m. Eastern: Jim Nantz, Phill Simms, Tracy Wolfson (field reporter). Westwood One: Kevin Kugler, Mark Malone SIRIUS: 88 (WestWood1), 83 (Seattle), 93 (San Francisco). XM: 88 (WestWood1), 225 (Seattle), 226 (San Francisco).

Injury Report

OUT: RB Derrick Coleman (Concussion), DT Jordan Hill (Quad), C Patrick Lewis (Ankle), LB Nicholas Moody (Ankle), CB Marcus Burley (Hand)
QUESTIONABLE: DE Demarcus Dobbs (Shoulder)
PROBABLE: DE Clifford Avril (Ankle), G Justin Britt (Hip), S Kameron Chancellor (Shoulder), DE Frank Clark (Hamstring), T Garry Gilliam (Ankle), WR Tyler Lockett (Hip), RB Marshawn Lynch (Hamstring), CB Richard Sherman (Ankle), CB Tye Smith (Hip), LB Bobby Wagner (Pectoral)

San Francisco
QUESTIONABLE: WR Anquan Boldin (Hamstring), RB Carlos Hyde (Foot), T Erik Pears (Back)
PROBABLE: G Alexander Boone (Shoulder), LB Navorro Bowman (Shoulder), LB Ahmad Brooks (Shoulder), RB Reggie Bush (Calf), TE Vernon Davis (Knee), WR Bruce Ellington (Calf), TE Vance McDonald (Chest), S Eric Reid (Chest), T Joe Staley (Knee), G Brandon Thomas (Ankle)

Weather Report: Mostly cloudy and 55 degrees.

Broadcast information and injury report courtesy the National Football League, odds courtesy Don Best and USA Today, weather information courtesy The Weather Channel.